Pharmacological Sciences

Pharmacological Sciences


Host Department
Department of Pharmaceutical and Pharmacological Sciences



Research Topic A

Abstract of the proposed UNIPhD research project


The prevalence of atrial fibrillation (AF) grows among Europe’s older population. AF is an abnormal heart rhythm with rapid and irregular beating that is associated with more severe strokes. The principal goal of AFFIRMO is to validate the effectiveness of a patient-centred, stratified care pathway for older patients with multimorbidity to facilitate a multidisciplinary, shared decision-making process. Improving AF management in the context of multimorbidity is critical and demands a comprehensive approach based on the “Atrial Fibrillation Better Care” (ABC) model.

In my research project I will work on the University of Padova database, which included data from 777 patients. While follow-up and data collection from geriatric patients with non-valvular AF (NVAF) is ongoing, descriptive data analysis was performed, involving patients’ demographics (i.e., age, gender), characteristics (i.e., height, weight, BMI), chronic diseases, anticoagulant therapy, biochemical analysis, drugs, and outcomes (haemorrhage, type of haemorrhage etc.). Moreover, the CHA 2 DS 2 – ASc and HAS-BLED scores were calculated, which are the standards for assessing the risk of stroke and haemorrhage, respectively. The study findings, with these data, can be beneficial in the evaluation of individual baseline risk profiles, leading to improved clinical decision-making, research, and policy for this patient populations.


Short bio

Dilek Celik is a UNIPhD Fellow in Pharmacological Sciences at the University of Padova, with a bachelor’s degree in Bioengineering and master’s degrees in Bioengineering and Public Health. After completing a patented project in the field of bone tissue engineering during her M.Sc. Bioengineering, she was awarded a scholarship by the Ministry of National Education of Turkey to pursue a master’s degree in Public Health at the University of Birmingham in the UK.
Celik has diverse industry experience in medical and pharmaceutical companies, along with academic experience as a lecturer. Her doctoral research, supervised by Professor Nicola Ferri, focuses on an integrated approach to atrial fibrillation (AF) in the frail, multimorbid, and polymedicated elderly.

Topic assigned to
Dilek Celik


Project documents